The micro-age is the one with micro-blog as the representative of communicative medium, and with shortness and refinement as the feature of cultural communication, in which the information communication is at a faster speed, and the communicative contents are more striking and heart-shaking. Socialist core value system decides the developmental direction of socialism with Chinese characteristics. However, the timely, autonomic, fissile, and fractional features in the communication of micro-age have put forward new challenges for the communication of socialist core value system in universities. Thus, we should establish the interactive mechanism between the ideological and political education class and the new media of the micro-age; we should pay attention to the opinion leader and give a full play to their positive energy; we should strengthen to build the communication teams of socialist core value system, and improve the communication efficiency of socialist core value system in universities.