Cultural ecology is the existence of human being, who is the existence of cultural ecology. Both college teachers and students, and college campuses constitute the cultural ecology. The core idea of humanistic quality education is peopleoriented. However, it does not reflect the people oriented conception. Humanistic quality education has been misinterpreted and deviated, which leads the educational practice to be astray. Only through studying and enhancing the humanistic quality education from the perspective of cultural ecology can the colleges humanistic quality education go smooth. From clarifying the relation between human being and nature, history, society, and oneself, we shall improve and strengthen the colleges humanistic quality education, guide and promote the college students to understand the ecological culture and history, pursue for the harmonious society, and realize selfharmony. Only in this way can the college students be truly humanistic qualified.